Материал: MasterPass _ Pharmacology in 7 Days for Medical Students

CLASSIFICATIONS

3Fibric acid derivatives

•Bezafibrate

•Fenofibrate

•Gemfibrozil

4Inhibitors of intestinal sterol absorption

•Ezetimibe

5Niacin (nicotinic acid)

H1-receptor antagonists (antihistaminics)

AFirst generation

1Alkylamines

•Chlorpheniramine maleate

•Pheniramine maleate

•Triprolidine HCl

2Ethanolamines

•Clemastine fumarate

•Dimenhydrinate

•Diphenhydramine HCl

3Ethylene diamines

•Antazoline HCl

•Methapyrilene HCl

•Mepyramine maleate

•Tripelennamine citrate

4Piperazines

•Buclizine

•Cyclizine HCl

•Chlorcyclizine HCl

•Hydroxyzine HCl

•Meclizine HCl

5Phenothiazines

•Dimethothiazine mesylate

•Methdilazine HCl

•Promethazine theoclate

•Trimeprazine tartarate

6Piperidines

•Astemizole

•Cyproheptadine hydrochloride

•Phenindamine tartarate

•Terfenadine

7Miscellaneous

•Doxepine hydrochloride

•Mebhydrolin napadisylate

BSecond generation

1Alkylamines (acrivastine)

2Piperazines (cetrizine hydrochloride)

3Piperidines (fexofenadine, loratadine)

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PHARMACOLOGY IN 7 DAYS FOR MEDICAL STUDENTS

General anaesthetics

IInhalational GA A Volatile liquids

1Older GA

•Ether

•Chloroform

2Halogenated GA

•Halothane

•Isoflurane

•Methoxyflurane

•Enflurane

•Desflurane

•Sevoflurane

BGases

•Nitrous oxide

•Xenon

•Cyclopropane

II Intravenous GA

1Barbiturates

•Thiopentone sodium

•Hexobarbitone

•Methohexitone

2Non-barbiturates

aPhencyclidine

•Ketamine

bBenzodiazepines

•Diazepam

•Lorazepam

•Midazolam

3Neuroleptic analgesia/anaesthesia

•Fentanyl

•Droperidol

4Opioid analgesics

•Morphine

•Alfentanil

•Remifentanil

•Sufentanil

5Miscellaneous drugs

•Propofol

•Etomidate

Local anaesthetics

1According to duration of action a Short DOA

•Procaine

bMedium DOA

•Cocaine

•Lidocaine

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CLASSIFICATIONS

•Mepivacaine

•Prilocaine

cLong DOA

•Tetracaine

•Bupivacaine

•Etidocaine

•Ropivacaine

2According to chemistry a Esters

•Cocaine

•Procaine

•Tetracaine

•Benzocaine

bAmides

•Bupivacaine

•Etidocaine

•Lidocaine

•Mepivacaine

•Prilocaine

•Ropivacaine

cEthers

•Pramoxine

dKetones

•Dyclonine

ePhenetidin derivatives

•Phenacaine

Narcotic (opioid) analgesics

ABased on source

1Naturally occurring opium alkaloids

•Morphine

•Codeine

2Semi-synthetic derivatives of opium alkaloids

•Diamorphine (heroin)

•Etorphine

•Hydromorphone

•Oxymorphone

•Hydrocodone

•Oxycodone

3Synthetic morphine substitutes a Pethidine and its congeners

•Fentanyl

•Sufentanil

•Alfentanil

•Diphenoxylate

•Loperamide

bMethadone and its congeners

•D-propoxyphene

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PHARMACOLOGY IN 7 DAYS FOR MEDICAL STUDENTS

cMorphinan compounds

•Levorphanol

dBenzomorphan compounds

•Pentazocine

•Cyclazocine

•Phenazocine

BBased on agonist-antagonist activities

iPure agonists

•Morphine

•Codeine

•Heroin

•Etorphine

•Fentanyl

•Pethidine

iiPure antagonists

•Naloxone

•Nalmefene

•Naltrexone

iiiMixed agonists-antagonists

•Pentazocine

•Cyclazocine

•Meptazinol

•Nalorphine

Penicillins

ANatural penicillins (narrow-spectrum, β-lactamase susceptible penicillins)

•Benzylpenicillin (penicillin ‘G’)

•Phenoxymethylpenicillin (penicillin ‘V’)

BSemi-synthetic penicillins

1Very narrow-spectrum, β-lactamase resistant penicillins

•Methicillin

•Nafcillin

•Oxacillin

•Dicloxacillin

•Flucloxacillin

2Extended spectrum, β-lactamase susceptible penicillins a Aminopenicillins

•Ampicillin

•Ampicillin pro-drugs (bacampicillin, pivampicillin, talampicillin)

•Amoxycillin alone, and with clavulanate (i.e. augmentin)

•Amoxycillin + flucloxacillin = magnapam

bAmidinopenicillins

•Mecillinam

•Pivmecillinam

cCarboxypenicillins

•Carbenicillin

•Ticarcillin

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CLASSIFICATIONS

dUreidopenicillins

•Azlocillin

•Mezlocillin

•Piperacillin

3Other β-lactam drugs

•Monobactam (aztreonam)

•Carbapenems (imipenem and meropenem)

4β-lactamase inhibitors

•Sulbactam

•Tazobactam

•Sodium or potassium clavulanate

Quinolones

1st Generation

•Cinoxacin

•Nalidixic acid

•Oxolinic acid

2nd Generation

AAgents with least activity against Gram –ve and Gram +ve bacteria

•Norfloxacin

BAgents with excellent activity against Gram –ve and moderate to good activity against Gram +ve bacteria

•Enoxacin

•Pefloxacin

•Ciprofloxacin

•Lenfloxacin

•Lomefloxacin

•Ofloxacin

CAgents with excellent activity against Gram –ve and improved activity against Gram +ve bacteria

•Gatifloxacin

•Moxyfloxacin

•Sparfloxacin

•Trovafloxacin

DAgents with additional activity against anaerobic bacteria

•Moxyfloxacin

•Trovafloxacin

Sedative-hypnotics (according to DOA)

ABarbiturates

iLong-acting

•Barbitone

•Methyl phenobarbitone

•Phenobarbitone

iiIntermediate-acting

•Amylobarbitone

•Butobarbitone

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